CD37 anticorps

N° du produit ABIN1106328

Cet anticorps anti-CD37 est un anticorps Souris Monoclonal détectant CD37 dans IHC (p), IHC (fro) et EIA. Adapté pour Humain.

Aperçu rapide pour CD37 anticorps (ABIN1106328)

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD37 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: IPO-24

Détail du produit anti-CD37 anticorps

Specificité: This antibody reacts with CD37 antigen (Human), 40-52 kDa glycoprotein. IPO-24 reacts with Human B cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are not labelled. IPO-24 stains B cell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrofils, macrophages, thymocytes and dendritic reticulum cells are negative.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: IPO-24 was generated after immunization of BALB/c mice with spleen cells of a patient with hairy cell leukemia. Mice splenocytes were fused with the P3-X63-Ag8.653 mouse myeloma cell line.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CD37

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Autre désignation: CD37

Sujet: CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD81, and the R2 antigen among others. Many of these molecules are expressed on leukocytes and have been implicated in signal transduction, cell to cell interactions, and cellular activation and development. The antigen CD37 defined by IPO-24 is B lineage restricted and is strongly expressed throughout B cell ontogeny from pre-B cells untill the plasmoblasts. CD37 is an extensively glycosylated molecule and usually two and sometimes three N-linked carbohydrate chain are attached to the protein. Synonyms: Leukocyte antigen CD37, TSPAN26, Tetraspanin-26

ID gène: 951

NCBI Accession: NP_001765

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response